The human body has many built-in regulating systems of checks and balances. And since Nitric Oxide is such a powerful compound, the Nitric Oxide pathway is one of the most complex. While arginine is the “raw material” used by the body to produce Nitric Oxide, there are many interactions along the Nitric Oxide pathway which influence Nitric Oxide production.
The Nitric Oxide biochemical pathway can be influenced by these various co-factors: homocysteine, ADMA (asymmetric dimethylarginine), SOA (super oxide anion), SOD (super oxide dimutase) and perhaps the most critical of all NOS (nitric oxide synthase). The relationship between these co-factors has a direct influence on the amount of arginine that can be converted (synthesized) to Nitric Oxide. Remember, no matter how much arginine or arginine substrates (i.e. AAKG, arginine malate, arginine ethyl ester) you feed your body, the amount of Nitric Oxide you can produce is limited to these Nitric Oxide pathway co-factors. The best way to explain it is that while arginine is the fuel, these co-factors are the parts which make up the Nitric Oxide engine.
Metafolin—The spark that ignites the Nitric Oxide engine!
Metafolin is an amazing newly discovered compound, patented by Merck KGaA Germany, which has the unique ability to maximize the conversion of arginine to NO by augmenting all of the co-factors involved in arginine’s conversion to Nitric Oxide within the pathway. The discovery of Metafolin, a powerful, novel compound, is regarded by many in the medical field as the biggest breakthrough ever in inducing Nitric Oxide production. Metafolin is so powerful, it is technically considered a drug even at low doses. And now, it’s being made available to bodybuilders and athletes exclusively in TRAC Extreme-NO.
Yes, Metafolin is the missing link scientists have been looking for to optimize L-Arginine’s conversion to Nitric Oxide. Combine Metafolin and Arginine and guess what you can expect—One Mother of a Pump! Scientists at MHP did not hold back in the formulation of TRAC Extreme-NO’s proprietary anabolic Nitric Oxide generator, Nitrofolin-ATP™. Each serving is loaded with a mega dose of 4 grams of pure pharmaceutical grade L-Arginine. This high dose L-Arginine with Metafolin combo by itself will blow away any other NO product in existence. But MHP scientists even went a step further and added 30 other proven Nitric Oxide and performance enhancement agents, making TRAC Extreme-NO the most powerful pump inducing pre-workout formula available. That’s not hype either—here’s the scientific explanation of how TRAC Extreme-NO will never be matched!
Crush NOS Inhibitors for Maximum Nitric Oxide Output
Earlier, we spoke about Metafolin’s unique ability to augment all the co-factors involved for the conversion of arginine to NO and we referred to NOS as the most critical of all—and here’s where most products lose their credibility in the scientific community and also fail to serve up fiber-swelling muscle pumps. Regardless of what NO imposters might be claiming in their advertising—no, the key is not AAKG, it’s not a Phylo-pseudo delivery technology, and it’s certainly not a ‘satellite’ cell, citrulline, arginine malate or arginine ethyl esther—the NO powerhouse is an enzymatic enigma called Nitric Oxide Synthase, or NOS for short. The reason you probably haven’t heard about it before lies in the fact that every Nitric Oxide product you’ve ever experimented with or read about fails to address it! This is a critical mistake on their behalf, because maximum Nitric Oxide production cannot happen without maximum NOS activity. Scientists refer to the NOS enzyme as a catalyst, a substance that increases the rate of a reaction. NOS is needed to convert arginine to Nitric Oxide; without NOS there is no conversion to Nitric Oxide regardless of how much arginine or other Nitric Oxide precursor you take. You can think of NOS as the “decision” maker with the power to decide whether or not you’re going to get the Nitric Oxide output you want for a maximum strength pump. NOS takes the NO precursors you’re consuming (hopefully it’s arginine and not some hyped up derivative) and converts it into Nitric Oxide. Sounds simple enough, right? But certain co-factors such as Homocysteine, ADMA (asymmetric dimethylarginine) and SOA (super oxide anion) are Nitric Oxide inhibitors. These inhibitors block and interfere with NOS, therefore restricting Nitric Oxide production.
It’s at this stage in the complex Nitric Oxide biochemical pathway that other NO products drop the ball—they simply fail to address these Nitric Oxide inhibitors that restrict Nitric Oxide production. Not anymore! With the discovery of Metafolin in combination with arginine and various other Nitric Oxide optimizers, MHP has been able to push Nitric Oxide production past all previous limits with their proprietary compound Nitrofolin-ATP. This allows athletes to finally harness the full power of Nitric Oxide for immense muscle pumps and to trigger new muscle fiber growth like never before. (See Illustration Below)
If you’ve ever taken a competitor's Nitric Oxide product, you've felt that 'flattening out' period and lost your pump quickly. Even with an extended release delivery, they broke their 'perpetual pump promise'. In fairness to them, even with a sustained or extended release delivery, keeping a maximum muscle pump isn’t happening unless you address a relatively unknown compound produced by your own body called, Phosphodiesterase-5 (PDE-5).
Here is how this 'pump killer' PDE-5 works. Biochemically speaking, the mighty Nitric Oxide molecule is available in your blood for only a few seconds even with a sustained release delivery.
Then it's converted into cGMP, a big driving force behind your pump. However, the sudden death of your pump occurs when the 'pump killer' PDE-5, converts cGMP into GMP—that little ‘c’ means everything—once cGMP is converted to GMP, it terminates the life of your pump…kiss your pump goodbye! In essence, even with an extended release delivery, the Nitric Oxide you are producing is getting shut down by PDE-5 as fast as you can make it—so you will never reach Nitric Oxide saturation or be able to keep your pump.
MHP R&D has employed an amazing new PDE-5 Antigen Technology with TRAC Extreme-NO that blocks PDE-5 from converting cGMP to the pump-deadly GMP, in effect, keeping the pump-feeding cGMP alive in your bloodstream for longer. With TRAC Extreme-NO, not only will you jack Nitric Oxide production through the roof with arginine, Metafolin and a full spectrum of other Nitric Oxide stimulators—with this new PDE-5 Antigen Technology, you’ll extend the lifespan of every Nitric Oxide molecule. The net effect of increased Nitric Oxide production coupled with the extended lifespan causes what is called ”Cumulative Nitric Oxide Saturation”. This maximum saturation of Nitric Oxide will actually force your muscles to expand giving you added size and an explosive pump that last for hours upon hours after your workout!
Fiber Splitting Pumps—Explosive Power—Insane Energy and Intensity
As promised, TRAC Extreme-NO doesn’t stop at the pump. TRAC Extreme-NO is the first supplement in the world to simultaneously master the Nitric Oxide pathway, biochemical energy cycle and mechanical power output system with its exclusive, patent pending NitroFolin-ATP™. We’ve clearly proven how TRAC Extreme-NO has set a new precedent in Nitric Oxide supplementation—it maximizes NO production and employs a host of powerful nutrients that combats all Nitric Oxide inhibitors and agonists, shutting them down dead in their tracks, allowing for uninhibited Nitric Oxide production within your muscle tissue. NitroFolin-ATP™ even increases the lifespan of the all-powerful Nitric Oxide compound with groundbreaking PDE-5 Antigen Technology for maximum Nitric Oxide saturation. But that’s not all…
NitroFolin-ATP™ will contribute to new gains in strength and muscle mass with an aggregate of the most heavily researched anabolic agents known to science, triggering explosive power and muscle cell expansion. NitroFolin-ATP also employs a hefty dose of energizing compounds to fuel your workouts with a high-powered Adrenaline rush that will have your tearing up the gym for the most intense workouts ever. And we all know how frustrating it is to have your muscles fill with lactic acid causing you to “hit the wall” and prevent you from pushing out those extra reps. NitroFolin-ATP allows you to push through “lactic acid burnout” and all plateaus with newly researched lac- tic acid buffering intermediates, which will allow you to overload your muscles more than ever—forcing you to tap into muscle fibers you never knew existed.
BiFusion-Two Stage On Demand Nutrient Delivery
To get the absolute most from this powerful compound, NitroFolin-ATP, MHP developed and patented the first ever “Two Stage On Demand Nutrient Delivery System” in TRAC Extreme-NO. A proprietary BiFusion Time Rele- ased Technology feeds these powerhouse nutrients to your muscles on demand, releasing them into your bloodstream when your body craves them most. So, take hold because your training is about to take on an entirely new dimension as you experience stage 1 of this technology. Instafusion, a quick insurgence of Nitric Oxide, ATP, cell volumizers and energizers that flood your muscles during your workout, allowing you to reach Maximum Muscle Nutrient Capacity for the most incredible strength, pumps and intense workouts imaginable. Then stage 2, Profusion, kicks in with a continual feed of Nitric Oxide, ATP and cell volumizers to stimulate muscle growth, recovery and keep you pumped for hours. Isn’t it time for you to take Muscle Growth, Intensity and “The Pump” to the Extreme! Get TRAC Extreme-NO!
Not worth the money Tried this product and stacked it with my pre workout. I felt no difference in pump compared to just taking my preworkout. Reviewer: Adam from | Date: 12/8/2014 5:20:09 PM
3 out of 5
MHP Up Your Mass I use this prorien powder several differnt times a day but mostly before bed, because of the multiple protien source they use allowing it to digest over 8 hours. whey, egg ebleim, and most importany casein protiens plus a mix of quility aminos glutimine and creatine that all help you grow while you rest. plus it tasts graet just by shaking it up in a shaker. Reviewer: salsprix from | Date: 1/14/2011
5 out of 5
great best weight gainer ever mmm the fudge brownie tastes so good Reviewer: john from brooklyn,ny | Date: 2/25/2007