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A Highly Advanced, Pharmacological Approach to Fat Annihilation!
Beta-Methoxy- Phenylethylamine is the newest compound on the dieting circuit that is offering the most promising results. In fact, researchers are saying that it offers more promising results than ephedra. Scientists have been studying this compound for years, but due to its short half-life it was never considered anything that could be effective. Attempts have been made with Beta-Methoxy- Phenylethylamine and MAO inhibitors to fix this problem, but things just didn’t work out. There is a new form though that is showing amazing result! Beta-Methoxy- Phenylethylamine is stomping out fat left and right, but to make sure that it could truly knock out this pesky problem a few added ingredients have been mixed in to simply annihilate any fat that is in its way.
Dren uses a scientific approach that is as able to trigger lipolysis for maximum fat burning. Dren is part of a powerful class of compounds that are known as mesolimbic Beta Agonist Fat Burning Agents. This can only be compared to the ECA stack of ephedra, caffeine, and aspirin. In addition to the thermogenic effects, Dren is able to offer psycho-active euphoric effects.
The benefits to this amazing supplement can be explained in four main steps, which are listed below for your convenience.
Step 1: Sympathometic Thermogenic Activation
Beta-Methoxy Phenylethlyamine, which is also called Beta-Methoxy PEA, is a new ingredient that is exclusive to Dren. Beta-Methoxy PEA is able to increase the noradrenaline release from the sympathetic nerve terminals. Beta-Methoxy PEA is able to stimulate the sympathetic nervous system. This is done by causing the pre-synaptic nerve terminals to release norepinephrine into the synaptic space. In addition to all of this it has the ability to increase circulating adrenaline, which is the body’s chief beta-2 agonist. Once it is released into the synaptic space, noradrenaline interacts with adrenergic receptors on the surface of fat. This starts a sequence of events in the adipocyte that bumps up the lipolysis by the enzyme hormone sensitive lipase. This fat burning effect is dependent on a long activation of the receptor by the agonist and it’s what makes Beta-Methoxy PEA so important. This is why it is more effective than other similar formulas.
Beta-Methoxy PEA is the top of the line in B-PEA beta-agonist. This is because of its long half-life and its affinity to be absorbed in fat tissue. This allows it more of a chance to permeate the blood/brain barrier. When you compare the half-life of other Beta-PEA forms the results are much different. In other forms there are only minutes for the enzyme MAO-B to be able to metabolize and they are less lipophilic which stops necessary concentrations from reaching the brain. This means there are no psychoactive or weight loss effect achieved. As it has been mentioned in the past, the addition of MAO-inhibitors should help, but the evidence that has been presented does not seem to show that as a fact.
Beta-Methoxy PEA is not broken down by MAO-B thanks to the unique way in which Beta-Methoxy PEA has been configured. The beta “Methoxy” moiety on the compound protects and allows for a higher level of absorption throughout the blood brain barrier, as well as ensuring deep penetration in the fatty tissues of the brain where it interacts with the aDrenergic receptors. This boost in noradrenaline and adrenergic receptors activation will increase cAMP levels in fat cells and in muscle cells.
Beta-Methoxy-PEA’s moiety is what helps give it that long acting force and its unique ability to get into fat tissue to initiate those strong fat burning effects. Methoxy is the key to the wonder in Beta-Methoxy-PEA and no matter what you might hear it is only found in Dren.
As if all of this was not enough, Beta-Methoxy Phenethylamine offers enhanced moiety that is able to get into the blood barrier, which produces an intense euphoric feeling.
Beta-Methoxy-PEA is both an alkaloid and a monoamine. This means that it has the ability to function as a neuromodulator or neurotransmitter. The results are an extreme psychoactive effect on the body and a fat burning rate that is not seen in other products! Beta-Methoxy Phenethylamine enters the brain barrier, which triggers a trickling release of norepinephrine, dopamine and serotonin and even stimulates the mesolimbic reward pathway. This manages to cause a euphoric attitude.
Step 2: The Addition of an Alpha 2 Agonist helps to further Enhance Beta-Methoxy PEA fat burning!
On its own, Beta-Methoxy-PEA is an amazing compound that offers a remarkable thermogenic effect. However, the scientists at MHP wanted to move fat burning to the next level. While part of the reason may have been to find a supplement as effective as ephedra, but that is not banned by the FDA, the real driving force to find this compound came from the need to move beyond the ECA stack. Once Beta-Methoxy-PEA was isolated it was possible to see that this compound has the chance to blow ephedra out of the water and the rest was history in the making.
The negative feedback mechanisms are able to reach activation as a response of the Beta-Methoxy-PEA’s beta-adrenergic stimulation. This feedback has the ability to shut down fat burning. The alpha 2 receptor, phosphodiesterases and adenosine attempt to slow down or stop the fat burning process.
In the case of Dren, Beta-Methoxy-PEA undergoes these negative feedback mechanisms. Therefore, measures had to be taken to maximize Beta-Methoxy-PEA’s actions in the body and minimize these negative feedback mechanisms.
Every form of Beta-PEA is considered to be non-selective adrenergics that works through the release of noradrenaline because they activate more than one type of receptor. Unfortunately, noradrenaline functions as a negative feedback signal by activating the beta and the alpha adrenergic receptors. The stimulation of beta receptors is good because it initiates the fat burning process. Meanwhile, the Alpha 2 receptors actually shut down lipolysis. The scientists at MHP have added Yohimbine to the Dren formula in order to bypass the Alpha 2 receptor binding, and to increase the effectiveness of Dren as a whole.
Yohimbine HCL is actually a selective alpha 2 antagonist. This means that it has the ability to short circuit the feedback loop and maximizes the levels of noradrenaline and the fat loss actions that come from Beta-Methoxy PEA. This mechanism of action offers a long acting activation on the beta receptor level and no activity on the alpha receptor. The result is the most powerful thermogenic activity that has ever been found in adipose tissue.
Step 3: Phosphodiesterase Inhibitibiton and Adenosine Receptor Interference
Caffeine is popular because of the stimulatory and the energizing effects that it offers. However, caffeine has a much more important role when it is offered in Dren. When the Beta-adrenergic receptor is stimulated it means that phosphodiesterase and adenosine activity will also increase. Phosphodiesterase (PDE) is able to hydrolyze cAMP into inactive fragments while adenosine inhibits cAMP accumulation by stopping the stimulation of HSL and the fat burning process altogether. The caffeine has the ability to inhibit phosphodiesterases in the cell and even has the ability to stop some of the re-uptake of norepinephrine while acting as an adenosine receptor blocker. Naturally, as you have seen here, caffeine is a necessary part that of Dren that provides important synergies to push Dren’s fat burning effects to new levels.
Step 4: Powerful Psycho-active Neurostimulation
Dren is such a special supplement because it not only transforms your body by burning fat, but it transforms your mind. Dren has the ability to make you feel like you are on top of the world! Beta-Methoxy-PEA is a psycho-active compound that triggers a sense of euphoria. To enhance the Dren neuromodulator activity, L-5-Hydroxytryptophan has been added into the mix. L-5-Hydroxytryptophan naturally occurs in amino acids, which is a precursor to the neurotransmitter serotonin. Serotonin is a monoamine neurotransmitter that has that feel good quality and it offers a strong appetite suppressant to enhance the overall effects. L-5-Hydroxtryptophan like Beta-Methoxy-PEA passes through the blood brain barrier into the brain.
The psychoactive action is thought to be derived from the effect on serotonin synthesis that is found in the central nervous system tissue. A high supply of L-5-Hydroxytryptophan has the ability to cause the brain's serotonin-producing neurons while increasing production that leads to increased serotonin release. The serotoninergic system is able to lift mood, keep emotions up and stable, help sleep, and keep your appetite at bay. This helps to control a number of the most important behavioral and physiological functions that need extra attention when trying to lose weight. L-5-Hydroxytryptophan can help balance the serotonin and norepinephrine levels, which leads to an increase of metabolism and additional fat loss through synergistic actions with the other ingredients in Dren. In the end, you have the perfect feel good state.
The fact is that Dren belongs to an entirely new class of compounds that are known as mesolimbic beta agonists. These compounds offer extremely strong fat burning and euphoric activities and for this reason, they need to be taken with caution. Dren is able to stimulate the metabolic and the mesolimbic pathways, which makes for some extreme thermogenic fat burning and an overall sense of wellbeing.
Every Dren capsule provides 470mg of Drenbuterol. This means that you should only take one dose and it does not (and should not) need to be used with other stimulants. Dren should only be taken as directed. When it is taken in this manner it will help to potentiate the thermogenic fat burning, raise your energy, suppress your appetite, and bring on a stage of mental wellbeing unlike anything you have ever tried in the past!
Serving Size 1 Capsule
Servings per Container 30
Amount per Serving
Drenbuterol - 409mg
Mesolimbic Beta Agonist Complex:
[Caffeine, L-5 Hydroxytryptophan, Beta Methoxyphenylethylamine, Yohimbine HCL.]
Yellow Opaque Gelatin Capsule
For best results take one capsule per day. You should not consume more than one capsule in a 12 hour period. Do not exceed the recommended dosage.
You should not use this supplement if you have any pre-existing medical conditions. Only use as directed. Do not take more than the recommended dosage. You should not use if you are under the age of 18. You should speak to your doctor before use if you are pregnant, nursing, or taking prescription medication (MAOIs, Antidepressants, Aspirin, NSAIDs, Ephedrine based products, Pseudoephedrine, Phenylephrine, Synephrine, Caffeine, or any other Stimulant based products). This product does contain caffeine. You should not use caffeine in other sources when using this supplement. Speak to your doctor if you have any medical conditions, including, but not limited to, thyroid, heart, kidney, or liver disease, epileptic disorders, mental health issues, problems urinating, high blood pressure, diabetes, headaches, cardiac arrhythmia, glaucoma, or enlarged prostate. You should stop use two weeks before any scheduled surgeries and if you experience any dizziness, rapid heartbeat, shortness of breath or severe headaches.
* No claims found on this web page or in print have been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. No claim or opinion about weight loss, bodybuilding or general health on this web page is intended to be, nor should be construed to be, medical advice. Please consult with a healthcare professional before starting any weight loss diet or exercise program.