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Designer Supplements ActivaTe Xtreme
 

DISCONTINUED    

Designer Supplements ActivaTe Xtreme
 
120 Capsules
Retail Price: 
$67.99
Our Price: 
$34.95
Manufacturer: 
Package Quantity: 
120 Capsules
Serving Size: 
2 Capsules
Number of Servings: 
60


User Reviews:  
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Product Description

The Next Level of Testosterone Optimization & Estrogen Control!

ActivaTe Xtreme offers a massive evolution from the original ActivaTe. This new formula still harnesses the amazing power of Divanil, but ActivaTe Xtreme goes further by providing a higher level of testosterone enhancement, adaptogenic support and estrogenic control. This is the absolute future of testosterone optimization.

When ActivaTe was released just two years ago it signaled a change in the market when it came to testosterone enhancements. Until that point there had not been a natural compound that was so effective. Divanil, the compound in ActivaTe, is a lignin that is found naturally in the roots of stinging nettles. For this reason, high doses of this lignin had never before been seen in the supplement industry.

Now it is time to raise the bar with the release of ActivaTe Xtreme. Divanil is again used because it is a tried and tested compound that has been scientifically supported to enhance free testosterone by binding to the sex-hormone SHBG. However, ActivaTe Xtreme goes even further than the original formula. Icariin is a flavonol that has been found in epimedium extract. This is included for its testosterone mimetic properties, as well as for its ability to promote serum testosterone levels. Another first for Designer Supplements, which is in ActivaTe Xtreme is Basella alba. This ingredient is similar to spinach and has been shown to promote testosterone production in the testes, as well as helping to increase bodyweight. The prime combination of these three ingredients should allow for significant elevations in testosterone. This also includes the natural occurring phytochemical indole-3-carbinol, which is included to promote a healthy estrogen metabolism while countering any unwanted side effects. The final ingredient is rhodiola rosea, a classic adaptogen that has been included for its effects on combating fatigue and stress while regenerating ATP reserves and promoting both physical performance and endurance.

Testosterone is one of the most anabolic hormones in the body, giving rise to the primary sexual characteristics that are found in males (and occasionally in females), while functioning in secondary sexual development as well as day to day functions. The body is made of millions and millions of cells, many of which express the androgen receptor that androgens such as testosterone will attach to. When this binding occurs, the nucleus of the cell increases the synthesis of proteins and upregulates metabolic processes. The focus here from a body building standpoint is the protein synthesis that is necessary for repairing, creating, and expanding muscle tissue.

The actual release of testosterone is governed by luteinizing hormone (LH). LH informs the Leydig cells to secrete androgens, including testosterone. Once it has been released, testosterone is controlled by two of the brain’s key mechanisms, albumin and Sex Hormone-Binding Globulin (SHBG). Albumin is present in a higher concentration than SHBG1, and binds to a higher proportion of total testosterone. However, it is done at a lower affinity than SHBG. Due to this, albumin-bound testosterone can be rapidly split up to allow for androgen receptor binding and interaction. SHBG binds to estrogen, though the affinity for estradiol is low, whereas its affinity for testosterone and DHT (dihydrotestosterone) is very high.

In typical cases, less than 2% of your testosterone concentration is considered to be free (active). This testosterone is sometimes known as Bioavailable Testosterone. At least 50% of your circulating testosterone is bound to SHBG. The rest of the circulating testosterone is albumin-bound. SHBG-bound steroids cannot bind to androgen receptors, which is why even the highest levels of testosterone can be inactive and useless.

ActivaTe changed that by using Divanil, which binds to androgens such as DHT and testosterone by SHBG is significantly reduced because of the high affinity that Divanil has for SHBG. The results are a considerable increase in free testosterone that is manifested in a number of ways, including increased strength and size, along with body composition. It even offers improvements in your sleep cycle.

The effects of Divanil go much further than all of the listed benefits. Divanil also promotes NO by increasing eNOS (endothelial NO synthase). As NO is postulated as one of the key triggers for muscle cell proliferation and growth while promoting muscle pumps, ActivaTe Xtreme leads to fuller muscles that you can see, which provides a higher level of mental motivation.

Icariin: The Testosterone Mimetic
Icariin is a flavonol that is found in epimedium extracts known as horny goat weed. This extract has been used for hundreds of years in Chinese herbalism and was just recently elucidated as to how and why Icariin exerts such effects. Studies have shown that Icariin has testosterone mimetic properties.

Icariin exerts an effect like Divanil, where the NO levels are raised. This is done similarly, by increasing an expression of the NO Synthase enzyme. Icariin differs from Divanil by being able to inhibit all forms of the enzyme, Phosphodiesterase type 5 or PDE-5.

NO promotes blood flow by binding to an enzyme known as guanylyl cyclase, which catalyzes the conversion of Guarnosine Triphosphate (GTP) to 3’, 5’-cyclic Guanosine Monophosphate, otherwise known as cGMP. The cGMP signals the smooth muscle to relax, which promotes blood flow. It’s PDE-5’s job to breakdown this enzyme, and when it does, blood flow is essentially restricted.

Basella Alba
Also known as Ceylon spinach, Basella Alba is a leafy vegetable that is grown in tropical regions. One of the reasons that Basella Alba has been included is because it’s been shown to increase serum testosterone as well as bodyweight in rats. Additional research in vivo has demonstrated that basella alba appears to exert these effects by stimulating the Leydig cells directly in order to produce testosterone. It is assumed that Basella Alba has an affinity for binding to the LH/CG receptors.

Rhodiola Rosea: The Adaptogen
Adaptogens are able to balance the endocrine and the immune systems which help the body maintain a level of homseostasis, while achieving this effect without any negative effects on other biological systems. Classified as an adaptogen by herbalists, Rhodiola Rosea is one of the top choices of adaptogens and for a good reason. Rhodiola Rosea exerts a number of benefits via several different biochemical pathways.

Bodybuilders are able to benefit greatly from Rhodiola Rosea because of the specific effects on improving endurance, performance, and helping with recovery after a workout session. The purported mechanisms of these benefits appear to be increasing ATP production in the mitochondria of muscle cells through the energy of the cell that drives recuperative processes such as protein synthesis.

Rhodiola also has neural-cognitive effects, such as the ability to reduce mental fatigue and it also acts as a nootropic. These effects also manifest in other ways. It’s also likely due to Rhodiola being an inhibitor of an enzyme known as catechol-O-methyltransferase (COMT). COMP is important because it helps promote the activity of the main feel good hormones. Russian scientists have concluded that Rhodiola Rosea influences the activity of opioid peptides like beta-endorphins. This is done by activating opioids receptors.

Indole-3-Carbinol (I3C)
I3C is a naturally occurring phytochemical that is found in vegetables like broccoli. I3C is a powerful antioxidant and it supports the liver’s typical processes, such as toxin removal. When it comes to ActivaTe Xtreme the main interest in I3C is the effect of modulating estrogen metabolism. Estrogen metabolism is complex, but the most important thing to understand is that there are two bad metabolites involved in estrogen metabolism. These metabolites are 16-alpha-hydrocyestrone and 4-hyroxyestrone. Oral consumption of I3C has been shown to increase 2-hydroxylation and reduce 4-hydroxylation while increasing the ratio of 2-hydroxyestrone and 16-alpha-hydroxyestrone.

After the oral intake of I3C, the acidic conditions of the stomach begin to create metabolites such as 3,3’-diindolylmethane (DIM). Both I3C and DIM exert their effects on estrogen metabolism by promoting the phase 1 enzymes that are controlled by the cytochrome P450 system, as well as the enzymes involved in the phase II such as Glutathione-S-transferase. When these enzymes are enhanced, estrogen metabolism is optimized.

ActivaTe Xtreme has been made to promote testosterone release and enhance free testosterone availability. It also promotes ATP synthesis and optimizes estrogen metabolism. ActivaTe Xtreme is the absolute future of testosterone optimization. Giving ActivaTe Xtreme a shot will show you that everything has been setup to ensure you succeed!



Supplement Facts

Serving Size: 2 Capsules
Servings Per Container: 60

Amount Per Serving

Proprietary Blend - 1250mg
Divanil[3,4-Divanillyltetrahydrofuran (95%)], Rhodiola Rosea (3% Rosavins), Icarrin (Standardized 20% Extract Of Epimedium), Indole-3-Carbinol (I3C), Basella Alba PE (10:1)

Other Ingredients
Magnesium Stearate, Rice Powder, Gelatin



Directions

Take 1 serving 2-3 times per day. For best results, use for 4 to 8 weeks. Do not exceed 8 weeks of continuous use.



Warnings

For use as a dietary supplement only, by healthy adult males the age of 18 and over. Women and children should not use this product. Women who are pregnant or nursing should not use any nettle product (nettle can alter the menstrual cycle). Use this product responsibly; always consult a physician before using this or any other dietary supplement.




* No claims found on this web page or in print have been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. No claim or opinion about weight loss, bodybuilding or general health on this web page is intended to be, nor should be construed to be, medical advice. Please consult with a healthcare professional before starting any weight loss diet or exercise program.

 



 
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