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Nitric oxide is a colorless, free radical gas commonly found
in tissues of all mammals. It can also be prepared commercially
by passing air through an electric arc. NO2 acts as a signal
molecule in the nervous system, and it is an important neuro-messenger
in a number of vertebrate signal processes. It is also a weapon
against infections, a blood pressure regulator and a gatekeeper
of blood flow to different organs. Bone marrow cells readily
produce nitric oxide in response to inflammations.
This simple, common, air pollutant, which is formed when nitrogen
burns (think car exhaust fumes and power plants) became a
sensation when scientists discovered that it harnesses the
body's natural energy source: blood, to regulate cell function
throughout. The inner lining of blood vessels use Nitric Oxide to signal the surrounding smooth muscle to relax, thus dilating
the artery and increasing blood flow. Increased Nitric Oxide
production improves circulation to the body's vital organs,
including heart and brain. This is of interest to bodybuilders,
as increased blood flow will deliver more nutrients to muscles,
helping them to become larger when subject to stress.
From Contaminant to Health Requirement
NO2 is a very reactive, toxic gas with harmful effects on
the environment. It has been implicated in depletion of the
ozone layer, formation of photochemical smog, and acid rain.
Chemists and environmentalists in the 1980's commonly regarded
it as a nasty little molecule with a bad reputation. Since
then, scientists discovered that NO2 is essential for overall
health and well being in humans.
Key Bodybuilding Benefits of Nitric Oxide
Hemodilation
Nitric oxide supplements induce hemodilation, which is the
widening of the blood vessels in the skeletal muscles. Wider
blood vessels leads to amplified blood flow; more blood flow
within the muscles means faster muscle recovery, faster gains
in muscle mass, and increased strength and endurance. It also
creates the so-called "perpetual pump" that nitric
oxide supplements are becoming known for.
"Perpetual Pump"
Taking nitric oxide supplements can help you achieve a natural
"perpetual pump" - a muscle pump that remains in
its post-exercise, blood-engorged, rock-hard condition all
day long. Although the extent of this effect varies from person
to person, almost all nitric oxide users experience an overall
"hardening" of their muscles, which obviously improves
physique quality.
Muscle Fiber Twitch Acceleration
By increasing NO production through the use of nitric oxide supplements, you can naturally increase the maximum contractile
velocity of both your fast-twitch and slow-twitch muscle fibers.
For most people this means a significant increase in the overall
strength of each and every muscle group.
Increased Endurance Index (EI)
Current research shows that keto-acids, like the
ones found in nitric oxide supplements, can significantly
delay muscle fatigue and improve you Endurance Index (a measure
of the rate of increased endurance during work output). What
this means is that you can work out harder - for a longer
period of time - before reaching muscle fatigue. Many nitric
oxide users notice that they don't get tired as quickly during
sets and workouts.
Basically, nitrous oxide supplements solve 95% of the problems
of natural bodybuilding. They allow you to enjoy many of the
benefits of steroids without the dangers. You can experience
continuous gains in lean muscle mass, enjoy a perpetual pump,
lift more weight, recover from workouts faster, and have far
more effective workouts with less fatigue. Anyone who is interested
in experiencing these amazing benefits should give nitric
oxide supplements a try.
A Short History of Nitric Oxide
Robert F. Furchgott, Louis J. Ignarro and Ferid Murad jointly
received the Nobel Prize in Medicine in 1998 for their discoveries
concerning "nitric oxide as a signaling molecule in the
cardiovascular system."
Furchgott, a New York pharmacologist, studied the effect of
drugs on blood vessels, but discovered that sometimes the
same drug caused a contraction, and at other times a dilatation.
His experiments led him to conclude that the blood vessels
dilated because their surface cells produced an unknown signal
molecule that made their smooth muscle cells relax. His findings
led to a quest for the molecule.
Murad, an MD and pharmacologist, studied how nitroglycerin
and related compounds act. In 1977 he discovered that these
compounds release nitric oxide, which relaxes smooth muscle
cells. The idea that a gas could control important cellular
functions captivated him, and he speculated that other factors
such as hormones might also act through NO2. There was no
evidence to hold up this belief at the time.
Ignarro, a Los Angeles pharmacologist, participated in the
search for Furchgott's signal molecule. In 1986, after an
inspired series of analyses, he concluded that the molecule
was NO2, identifying Furchgott's factor and solving the problem.
This was the first discovery that a gas can act as a signal
molecule in the organism.
Other Uses for Nitric Oxide
Nitric Oxide is the key molecule for circulation, erection
and arousal. The popular drug Viagra contains Nitric Oxide,
essential for increasing blood flow to the penis.
NO gas has also been used in the treatment of intensive care
patients, especially infants with dangerously high blood pressure
in their lungs - a major cause of cardiorespiratory failure.
Dosage is critical since the gas can be poisonous at high
concentrations.
Nitric Oxide is important to you as a bodybuilder, and its
supplements carry a lot of marketing hype. Many of the companies
that produce it have no research to back their claims. So
when you're buying it, get it from a reputable company known
for making quality products.
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