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Increases Cell Volume - Maximizes Muscle Size And Strength!
Applied Nutriceuticals NeoVar Product Guide - Next Generation Creatine!
Applied Nutriceuticals has come up with a potent and effective post-workout nutrient enhancement formula. The main component is a precise, balanced combination of creatine monohydrate and phosphocreatine (Mono/PCr complex), this complex plays a crucial supporting role in energy production at the cell level by regenerating ATP in muscle tissue and using it for explosive exercises 1-5. NeoVar has another critical ingredient, Corosolic Acid , an herb that grows in India, Southeast Asia, and the Philippines and is taken from the Banaba plant. NeoVar's last innovative ingredient, D-Pinitol, has been shown to support increased nitric oxide production and nutrient sensitivity both key factors in the process of nutrient transport. Each ingredients individual impact work synergistically to have a significant impact on the size, strength, and endurance of your muscles.
The thinking behind the Mono/PCr Complex is really very simple:helping support greater absorption and utilization with minimal waste by matching the CRfree 40/PCr 60 ratio of the naturally occurring human intramuscular creatine pool as much as possible. This product includes creatine monohydrate as the active ingredient. It's also blended to maximize PCr levels. Human skeletal muscle creatine stores are 60% in the phosphorylated form, creatine phosphate (CP) and 40% in the free creatine form (CRfree). The NeoVar Mono/PCr complex supports both CRfree levels and phosphocreatine levels in this ideal ratio,chemically the same as in working muscles 1,3-5. Research on phosphate indicates several benefits in the field of athletics even without creatine, mainly from the standpoint of buffering lactic acid during explosive exercise. Phosphate supplementation is used to promote levels of 2,3-diphosphoglycerate (2,3-DPG), this is the enzyme that injects oxygen into muscle. Studies have shown that supplmenting with creatine phosphate helps raise blood levels of 2,3-DPG, as well as encouraging the use of glycogen for fuel. The blend of CRfree and PCr will allow muscle to assimilate the creatine in a way that allows a substantial amount of uptake enhancement in muscle tissue 32-38.
In developing NeoVar, we looked at every type of creatine available before we completed the product, such as analyzing the research regarding the benefits of each. What we discovered was that in reality many of the improvements reduced the effectiveness of the product!
Instead we decided to use the molecules used in human research so we could duplicate the exact physiological ratios found in human muscle tissue, this way the body would recognize and use it.
Over the years creatine has proven to be an effective anabolic supplement: it promotes increased lean mass and it's a source of ATP. Additionally, Increased creatine in the muscle results in greater intracellular water retention, increasing muscle size and allowing for increased nitrogen retention and protein synthesis, which supports an environment of muscle growth 2-4. As well, Creatine uptake has been shown to be influenced by glucose,which can allow for greater amounts of creatine to be stored in the muscle cells. The main goal of NeoVar- allowing for the most creatine to be stored in working muscle by manipulating different nutrients 1-6.
Most manufacturers recommend an initial loading dose to speed up creatine saturation in the cell; yet this approach can cause uncomfortable abdominal cramps and bloating. Back in the early 90´s research advised ingesting high glycemic carbohydrates such as dextrose with creatine to dramatically raise muscle concentrations beyond regular oral use alone. However, recent studies suggest taking creatine with glucose (25-100 g), or with combinations of glucose and protein (around 30-40 grams of each macronutrient), this can result in greater amounts of creatine storage because of the increased insulin release in response to the carbohydrate intake 1,5,6. Yet these techniques can fall short due to the fact that some of the creatine may not be completely absorbed. When developing NeoVar, we wanted to find other ingredients that could support a greater uptake of intramuscular creatine.
Bioperine (piperine 95%)
This is a cutting edge ingredient that helps promote the increased uptake of some nutrients and supplements. Extremely crucial in the NeoVar formula, Bioperine is an potent recovery and growth ingredient, because it may help the absorption of greater amounts of the other active ingredients in NeoVar. It's also been suggested that Bioperine can decrease the breakdown of numerous nutrients by the liver, allowing for larger amounts of active ingredients to stay in the bloodstream longer; which makes them more available for uptake by your hard-working muscles. 40-42.
The revolutionary ingredient D-Pinitol is an critical component of NeoVar, it's been shown that it stimulates glucose uptake to a level close to insulin 26-30. In a low insulin concentration, a synergistic effect was found between insulin and pinitol. As well, d-pinitol can promote increased glycogen synthesis in the muscle cells. Yet the primary reason D-Pinitol stands out is that it has been shown to increase creatine storage in humans. It has been shown that Creatine loading increases muscle creatine and phosphocreatine stores by 5 to 30% 1-4.
NeoVar combines the benefits of some of the most biologically available creatines with ingredients that transport them into your muscle cells efficiently and quickly. In convenient capsules, no other product can deliver like NeoVar - at any price.
Serving Size: 1 Capsule
Servings Per Container: 110
Amount Per Capsule
PCr-Mono Matrix™ (Proprietary Blend) - 646mg
Glucovar / Adenylate Cyclase Sensitization Complex (Proprietary Blend) - 104mg
Banaba Extract (Lagerstroemia Speciosa 1% Corosolic Acid)
Gymnema Sylvestre (75% Extract0
Bioperine (95% - 98% Piperine) Registered Trademark Of Sabinsa Corp. And Holds Patent # 5,536,506
Gelatin, Candurin® Silver Fine, FD&C Red #3, FD&C Yellow #5, FD&C Blue #1
Take immediately post-workout with carbohydrates, preferably sugars. Take second dose with any other meal throughout the day containing carbohysrates.
This product is only intended to be consumed by healthy adults 18 years of age or older. Do not use if you are pregnant or nursing. Before using product, seek advice from a physician if you are unaware of your current health condition or have any pre-existing medical condition including but not limited kidney disease or if you are taking any prescription or over the counter medication. Do not use if you are pregnant, nursing, prone to dehydration or exposed to excessive heat. Discontinue use and consult your health care professional if you experience any adverse reaction to this product. Before beginning any weight loss program, consult your health care provider. Keep Out Of Reach Of Children.
* No claims found on this web page or in print have been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. No claim or opinion about weight loss, bodybuilding or general health on this web page is intended to be, nor should be construed to be, medical advice. Please consult with a healthcare professional before starting any weight loss diet or exercise program.