Okay, now that we have given you Hyperdrive 3.0™ (you know the mega-energy-rapid calorie expenditure phenomenon) and Lean Dreams™ (sleep/relaxation and healthy GH modulator…because you can’t stay wired 24/7) it is time to introduce the final key to the Tri-Lean System™ appropriately called…Zero-Stim.
Zero-Stim is The highest standard by which all other stimulant free adipose inhibition and oxidation products should be measured by. (As in…it inhibits fat storage and aids burning the flab too) This new only from ALRI product makes your body burn fat by wasting calories at an accelerated rate while protecting lean tissue mass and supporting thyroid health….even while you are sitting on your butt! (Imagine adding the Tri-Lean™ training and diet system!) Zero-Stim can be used alone, or stacked with the rest of the Tri-Lean System™ and T-X™ for Super Charged “I want it today” results.
What makes this One Different from the Other ALRI™ Products?
Hey, it’s from ALRI. You already know the innovation and results will piss some wanna-be scientist off because it is new, it works and they don’t understand it.
Theobroma Cacao extract for 12% OEA (oleoylethanolamide) and 3-Thia-Palmitic Acid (Tetradecylthioacetic acid) are very cool compounds that promote lipolysis (blubber burning) through some unique pathways.
OEA is produced in the small intestine and belongs to a group of fats produced in response to nervous system activity and certain metabolic events.
In an interesting mammal study published in the Journal of Biological Chemistry, OEA was shown to reduce feeding and body weight gain by activating the nuclear receptor PPAR-alpha (peroxisome proliferator-activated receptor alpha). In the present report, we examined whether OEA can also influence energy utilization. OEA stimulated glycerol and fatty acid release from freshly dissociated rat adipocytes. OEA enhanced fatty acid oxidation in skeletal muscle strips, dissociated hepatocytes, and primary cardiomyocyte cultures. Administration of OEA in vivo produced lipolysis.
In short, the OEA study results showed a decrease in food intake and an increase in calorie expenditure by way of lipolysis and fat oxidation through a unique pathway. The same study left us with this quote to consider: “The results suggest that OEA stimulates fat utilization through activation of PPAR-alpha and that this effect may contribute to its anti-obesity actions”.
Then Why Add 3-Thia Palmitic Acid Too?
The Department of Clinical Biochemistry, Haukeland Hospital, University of Bergen, Norway did a study on 3-Thia fatty acids that resulted in conclusions anyone wanting to create and maintain a lean body would salivate over…
“The biological responses to tetradecylthioacetic acid include mitochondrial proliferation, increased catabolism of fatty acids, antiadiposity, improvement in insulin sensitivity, antioxidant properties, reduced proliferation and induction of apoptosis in rapidly proliferating cells, cell differentiation and antiinflammatory action.”
“These biological responses indicate that tetradecylthioacetic acid changes the plasma profile from atherogenic to cardioprotective. As a pan-peroxisome proliferator-activated receptor ligand, tetradecylthioacetic acid regulates the adipose tissue mass and the expression of lipid metabolizing enzymes, particularly those involved in catabolic pathways.”
1) Fat burning due to more mitochondria to do so and fat oxidation via our good friend PPAR-alpha.
2) Fat storage control.
3) Better insulin activity control so calories are stored as lean tissue instead of waist wrap for winter.
4) Anti-oxidant qualities to protect cells form the damage normally done by calorie restricted diets and training.
5) A cool hatred for cells that are not supposed to be mass produced.
6) Improved lipid metabolization.
So, Together, OEA and 3-Thia Palmitic Acid make for serious synergistic lipolytic action!
Cool, Now, How About Blocking Fat Storage?
Polygonum Multiflorum Proprietary Extract is one of the new sensations in the fat burning industry. The really hard part is actually creating the most effective proprietary extraction procedure to make it work and at a concentration that makes it possible to put in a capsule.
Polygonum Multiflorum Proprietary Extract has been used in herbal medicine for centuries for its reported ability to promote lipid control and aid cardiovascular health. Oh sure, there is a great deal of evidence that the extract acts as an anti-oxidant, anti-catabolic and nitric oxide potentiator in mammals, but more recently, and due to some pretty cool extraction methods…
It has been found that Polygonum Multiflorum Proprietary Extract has unique properties that inhibit anti-lipolytic hormone (the hormone that shuts down fat burning potential) and fatty acid synthase (the enzyme that is the gate keeper for fat storage).
As many fans of ALRI are aware, we love to use this and the next compound in many of our fat loss lean mass promoting products simply because they work so well.
Beta AET ECPE (beta-androstenetriol ECPE)? We have all heard, and in many cases experienced, the positive effects of DHEA and its even better metabolites. As example are the patented and effective products 7-OXO-DHEA and of course 7-Hydroxy-DHEA analogs. They are noted for their unique ability to avoid conversion into androgenic metabolites or affect androgen receptors while promoting fat loss, lean mass retention and even maximizing thyroid gland activity. Of course oral bio-availability is pretty poor with most of these analogs thus requiring higher dosages. Did I mention that bAET (b-androstenetriol) is between 100 and 100,000 times more active than its DHEA precursor metabolites? Okay, how about that bAET ECPE is nearly 100% orally bioavailable? Yup. It’s why we formulated it.
Glucocorticoids in humans are in two forms: Inactive cortisone and very active for eating muscle cortisol. There are two enzymes that are able to make each of these convert into the other.
11b-HSD-1: Converts inactive cortisone into cannibalistic cortisol. Studies have implicated this event in fat tissue as a pathway for increased fat storage. Part of the reason GH has a positive affect upon body composition is through its ability to inhibit 11b-HDS-1
11b-HSD-2: Converts nasty cortisol into cortisone. 11betaHSD2 debunks intracellular cortisol by 90%. (Let the 11b-HSD-2 rule the house)
Hmmm, more 11b-HSD-1 means more cortisol which eats more muscle. And less means…Duh!
Beta-AET ECPE inhibits the 11b-HSD-1 enzyme both locally and systemically. This means that there is less conversion of cortisone to cortisol in muscle as a result of training and everywhere else due to stress like dieting. Based upon the studies, it appears that in mediating this pathway, bAET ECPE increases immune function and recovery of cells as well. Add this to its stimulatory affect upon the thyroid gland to support natural thyroid hormone production? Yup, less cortisol, higher metabolic rate, inhibition of that nasty negative thyroid hormone production feed-back loop…less fat, more lean muscle and positive support to health. Not bad!
Clary Sage Extract has a really cool effect due to its cAMP stimulating value. There is a significant similarity between compounds in this interesting herb and Thyroid Stimulating Hormone (TSH). As most are aware, increased TSH means more fat burning anabolism promoting T-3 production (yes, it acts synergistically with the last goodie in this regard…but through different pathways).
The connection here is that the TSH-like effect triggers an enzyme called adenylate cyclase in the thyroid that results in an increase in cAMP activity and subsequently lots of extra T-3 production…naturally. Since there is an increase in cAMP, there is an accompanying increase in nitrogen retention.
We added Salvia Tanshinones to aid lipolysis via improved liver lipid metabolism, gallic acid to inhibit fat cell uptake of glucose, Oleanolic Acid to block fat absorption, Bergenin to enhance norepinephrine triggered lipolysis and Rhodiola to support mood and immune function.
What about Insulin Insensitivity and Fat?
One reason we accumulate fat is due to insulin. Insulin is likely one of the most anabolic to muscle substances on the planet, but it has an evil side in that it is anabolic to fat cells too. The reason is partitioning meaning that insulin can store calories in fat or muscle.
As we gain fat, muscle cells tend to become less sensitive to insulin (Insulin Insensitivity) and fat cells tend to become ever so accommodating. So the result is that fat get the lion’s share of calories coming in. When you diet or cut calorie intake the muscle start to shrink and the fat cells have the upper hand in the fight for calories which is why most lose more muscle than fat when dieting.
The goal is to stimulate muscle cell insulin sensitivity and decrease fat cell feeding frenzies… Repartitioning!
Punica granatum flower (PGF) has been used as an anti-diabetic medicine in Unani medicinal literature. In several studies the reported active compound in this friendly herb that causes this cool event is gallic acid. You are already aware of the research that shows gallic acid inhibits fat cell feeding on glucose, but the right extraction has been shown in mammal studies to induce muscle cell insulin sensitivity. When fat is starved and muscle is fed…well, you do the math.
So fat lipolysis with fat storage inhibition on multiple levels and repartitioning to support lean tissue...now you get the “Zero-Stim” part?
Zero-Stim is the ultimate stimulant free stand alone or stackable synergistic supplement for any serious fat loss system!
Two capsules supply the following ingredients:
Servings Per Container: 60
Stimulant Free Proprietary Matrix - 750mg
Theobroma cacao ext. 12% OEA, polygonum, multiflorum proprietary extract, 3-thia palmitic acid, berginin, green tea extract 45% EGCG, gallic acid, rhodial rosea ext. 4% rosavins, hoodia gordonii 25:1, oleanolic acid, salvia miltiorrhiza ex 40%, tanshinones, clary sage extract bAET ECPE, piperine.
Other Ingredients: Modified cellulose (vegetable capsule), cellulose, magnesium stearate.
Take 2 capsules 2 times daily with food.
Not for use by those under 21 years old. Do not use if pregnant or nursing. Keep out of reach of children. Do not consume this product if you have a medical condition and/or taking any prescription medication. Do not exceed recommended serving. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, severe headache, or other similar symptoms.
* No claims found on this web page or in print have been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. No claim or opinion about weight loss, bodybuilding or general health on this web page is intended to be, nor should be construed to be, medical advice. Please consult with a healthcare professional before starting any weight loss diet or exercise program.